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Chemical Structure : Sisunatovir
CAS No.: 1903763-82-5
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RV521(Sisunatovir)
Catalog No.: URK-V607Â Â Only Used For Lab.
RV521 (Sisunatovir) is a potent, orally active, small-molecule inhibitor of RSV fusion, demonstrates potent antiviral activity across multiple strains of RSV in vitro..
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Biological ActivityRV521 (Sisunatovir) is a potent, orally active, small-molecule inhibitor of RSV fusion, demonstrates potent antiviral activity across multiple strains of RSV in vitro.
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Physicochemical Properties|
M.Wt |
446.45 |
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Formula |
C23H22F4N4O |
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CAS No. |
1903763-82-5 |
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Storage |
Solide Powder -20 °C 3years; 4°C 2years |
In Solvent -80°C 6 Months -20°C 1 Months |
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Solubility |
10 mM in DMSO |
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Chemical Name |
1'-((5-(aminomethyl)-1-(4,4,4-trifluorobutyl)-1H-benzo[d]imidazol-2-yl)methyl)-6'-fluorospiro[cyclopropane-1,3'-indolin]-2'-one |
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References
1. Yu-Ki Tahara, et al. J Am Chem Soc. 2018 Feb 14;140(6):2105-2114.
2. Qin S, et al. J Immunol. 2020 Oct 15;205(8):2231-2242.
3. Zhang L, et al. Redox Biol. 2021 Apr;40:101848.
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